Iingxaki kunye neNkqubo yokuPhuculwa koBuqhophololo boMtyalo kwiFoil yeAluminiyam ye-Pharmaceutical
Ifoyile ye-aluminiyam exutywayo yimathiriyeli ebalulekileyo ekupakishweni kwechiza, isetyenziswa kakhulu kwipakethe yamadyunguza kwiifom zedosi eqinileyo kunye nokutywinwa kwezikhongozeli zokungena ngenxa yeempawu zayo ezintle zomqobo., umsebenzi wokutywina, kunye nokhuseleko. Umgangatho wokugquma uchaphazela ngokuthe ngqo ukuzinza kokugcinwa, ukhuseleko lokusetyenziswa, kunye nokupakishwa kokuthotyelwa kwamayeza. Ukwaleka brittleness, enye yezona ziphene ezisemgangathweni eziqhelekileyo kwimveliso kunye nokusetyenziswa kwefoyile ye-aluminiyam yamayeza, ayigcini nje ngokulalanisa ukusebenza komqobo, okukhokelela ekufunxeni kokufuma, oxidation, kunye nokungcoliseka kweziyobisi, kodwa inokwazisa iingozi zokhuseleko ngenxa yokuvalelwa kwamaqhekeza okwambathisa.
1. Ubume beNgxaki kunye neeNgozi zokuBoneka kweCoating
1.1 Iifom zoBubrittleness
Ubuqhophololo bubonakala ngokuyintloko njengeentanda, iqela, okanye umgubo wokwaleka kwizigaba ezahlukeneyo, ezinokuthi zihlulwe zibe ziindidi ezintathu:
1.1.1 Ubuqhophololo Ngexesha Lokuvelisa
Ukuqhekeka komphezulu kubonakala ngokukhawuleza emva kokutyabeka kunye nokunyanga, okanye i-brittleness yenzeka emiphethweni ngexesha lokukrolwa okanye ukujija ngenxa yoxinzelelo.
1.1.2 Ubuqhophololo Ngexesha lokuGcina nokuThutha
Ubuqhophololo buvela ngenxa yokuguquguquka kobushushu kunye nokufuma okanye uxinzelelo lwangaphandle, enokuthi ihambe kunye nomonakalo we-substrate.
1.1.3 Ubunzima ngexesha lokusetyenziswa
I-coating iyahlukana ngokulula, iipowders, okanye ude ukrazule kumaphepha ngexesha lokubethelwa kwe-blister okanye ukuvulwa kwesigulana.
NgokoMthetho Jikelele 4055 ye Pharmacopoeia yaseTshayina2025 Uhlelo, ukuqaqanjelwa ngokuthe ngqo kubangela ukugqabhuka kwamandla okuwela ngaphantsi kwemfuneko esemgangathweni (≥98 kPa). Iisampulu ezinqabileyo zihlala zibonisa amandla agqabhukileyo ngezantsi 60 kPa, ngelixa umphunga wamanzi kunye namazinga okuhanjiswa kwe-oksijini ethanda ukudlula imida, ukubeka esichengeni ukhuseleko lweziyobisi.
Itafile 1: Iimpawu eziphambili kunye neempembelelo zoKutyabeka ngobuqhophololo kwiFoyile yeAluminiyam yezamayeza
| Inqanaba lokuKhanya | Iimpawu eziqhelekileyo | Iimpawu zeMpembelelo ePhambili | Imiphumo Enokubakho |
|---|---|---|---|
| Inkqubo yeMveliso | Ukuqhekeka komphezulu emva kokugquma; Ubunzima bomphetho ngexesha lokuqhawula / ukujika | Amandla okuqhuma, ukunamathela kokugquma | Imveliso yezilahlwa kwangoko, ukwanda kweendleko zemveliso |
| Ugcino & Ukuthutha | I-Delamination, iintanda, iqela lasekuhlaleni | Inqanaba lokuhambisa amanzi e-vapor, Inqanaba lokuhambisa ioksijini | Ilahleko yeempawu zomqobo, okukhokelela ekufunxeni kokufuma kunye ne-oxidation |
| Inkqubo yokusetyenziswa | Umgubo ngexesha lokubetha, ukukrazula ngexesha lokuvula | Imbonakalo, ingqibelelo yokwaleka | Umngcipheko wokungeniswa kwemiba yangaphandle, echaphazela ukhuseleko lweziyobisi kunye namava omsebenzisi |
| Iimpembelelo eziqhelekileyo | Ukwaleka okungaphelelanga, iziphene ezibonakalayo okanye ezincinci | Amandla okuqhuma (rhoqo <60 kPa), ukusebenza komqobo | Ukungahambelani ne Pharmacopoeia yaseTshayinaimigangatho, ukubangela imingcipheko yolawulo |
1.2 Iingozi eziphambili zoBubrittleness
1.2.1 Imingcipheko yoKhuseleko lweZiyobisi
Iingceba zokugquma zisenokosulela iziyobisi; iipropati zomqobo ezincitshisiweyo zinokukhokelela ekufunxeni komswakama, oxidation, kunye nokuthotywa, ngakumbi achaphazela ukukhanya kunye namachiza asebenzisa i-hygroscopic. Uphononongo lubonisa ukuba ukupakishwa okuneziphene ezi brittle kunokonyusa umthamo wokufuma kwechiza ngomndilili we 2.3% emva 6 iinyanga zovavanyo olukhawulezileyo (40°C/75% RH), ngaphaya kwemigangatho ye-pharmacopoeial.
1.2.2 Ukuthotyelwa kunye nemingcipheko yoMgangatho
I-Coating brittleness sisiphoso esinzima somgangatho esilelayo ukuhlangabezana nemigangatho efana ne Pharmacopoeia yaseTshayinakwaye Ifoyile yeAluminiyam yezamayeza(YBB00152002-2015), okunokuba nesiphumo sokungaphumeleli kokubhaliswa kwemveliso, Ukungahambelani nophicotho lwe-GMP, Imveliso ikhumbula, kunye nezohlwayo zolawulo. Ukususela ekuphunyezweni kwenkqubo yophononongo enxulumeneyo, malunga 18% abavelisi befoyile ye-aluminiyam baye bapheliswa ngenxa yemiba yomgangatho wokugquma.
1.2.3 Imingcipheko yoQoqosho kunye neBrand
Ukunyuka kwamazinga alahlwayo kunyusa iindleko zemveliso; imiba umgangatho ukonakalisa isidima corporate kunye nobudlelwane abathengi. Ngaphantsi koxinzelelo lweendlela zokuthengwa kwempahla eluhlaza, iinkampani ezinomgangatho ophantsi zijongelwa phantsi kwimarike.
2. Uhlahlelo lweMbango loBuqhophololo beCoating
Oonobangela bobuqhophololo babandakanya izinto ezininzi, kuquka imathiriyeli ekrwada, iinkqubo, unyango lwangaphambili, kunye neemeko zokusingqongileyo, zonke ziyahambelana.
Itafile 2: Uhlalutyo lweMbango ePhambili yoBuqhophololo boBuqhophololo kwiFoil yeAluminiyam ye-Pharmaceutical
| Category Cause | Imiba ethile | Indlela yokwenza | IiMbonakaliso eziqhelekileyo okanye iiParameters ezimbi |
|---|---|---|---|
| Ukunganelanga kweMathiriyeli ekrwada | 1. Iziphene zomgangatho wesubstrate | Ukwaleka okungalinganiyo, uxinzelelo loxinzelelo; ukuncamathela kakubi | Ukucoceka okuphantsi, ukunyamezela ubunzima >±2μm, ukungcoliseka komphezulu |
| 2. Ukukhethwa kwe-resin engafanelekanga | Ukuguquguquka kokutyabeka okungalunganga, ukuqina okuphezulu | Ubushushu beglasi obuphezulu benguqu (>50°C), ukusabalalisa ubunzima bemolekyuli ebanzi | |
| 3. Ukusetyenziswa kokongeza okungafanelekanga | Ukwanda koxinzelelo lwangaphakathi, ukungahambelani kakuhle | I-plasticizer ratio engafanelekanga, intsalela ye-solvent ephezulu | |
| Iinkqubo zeMveliso ezingafanelekanga | 1. Ukutenxa kwiparamitha yokwaleka | Ubunzima bokwaleka obungalinganiyo, isizukulwana soxinzelelo lwangaphakathi | Isantya esigqithisileyo, ukutenxa ubukhulu >± 3% |
| 2. Ulawulo olulambathayo lwenkqubo yokunyanga | Uxinaniso olungafanelekanga lokudibanisa, ubrittle kakhulu okanye amandla angonelanga | Ubushushu/ixesha elingalunganga, ukuchaneka kwe-UV engalinganiyo | |
| 3. Ukunqunyulwa okungafanelekanga kunye nokujika | Uxinzelelo lwe-Edge okanye uxinzelelo oluqhubekayo | Uxinzelelo olugqithisileyo, isantya sokuqhawula ngokugqithisileyo | |
| Ukungonelanga kweSubstrate Pretreatment | Ukungacoceki kunye noburhabaxa | Ukunamathela obuthathaka bokugquma, utyekele kwi-delamination | Ukusula okulula kuphela, amandla angaphezulu <35 mN/m |
| Imiba yokusingqongileyo | Ukuguquguquka okugqithisileyo kobushushu/ukufuma okanye ukucoceka okulambathayo | Uxinzelelo lobushushu, ukunyangwa kakubi, ukungcola intshayelelo | Ubushushu <15°C, umswakama >80%, ungcoliseko lothuli |
2.1 Ukunganelanga kweMathiriyeli ekrwada
2.1.1 Iziphene ze-Aluminiyam yeFoil Substrate
Iisubstrates (I-E.G., 8011, 8021 izabelo) ngobunyulu obuphantsi, ukungcola okuphezulu, flatness embi, okanye ukunyamezela ubukhulu obugqithisileyo (>± 2 μm) kunokukhokelela kwi-coating engalinganiyo kunye noxinzelelo loxinzelelo. Amabala e-oyile engaphezulu okanye amaleko eoksidi angqindilili ngokugqithisileyo nawo anciphisa ukuncamathela kokutyabeka.
2.1.2 UKhetho lweResin yokugquma ngokungafanelekanga
Iirasi eziqhelekileyo (I-E.G., acrylic, i-polyurethane, I-Eva) nokubhetyebhetye kakubi, amaqondo obushushu beglasi aphezulu kakhulu (I-E.G., >50°C), okanye ukusabalalisa ubunzima bemolekyuli ebanzi kunokubangela ukuqina okuphezulu emva kokunyanga. Ukunyibilika kwesalathiso sokuguquguquka kweereyini zetywina lobushushu ezingaphezulu kwe ±15% nako konyusa umngcipheko wokonakala..
2.1.3 Usetyenziso oloNgezelelweyo olungafanelekanga
Izixa ezingafanelekanga zeeplastiki, ukungahambi kakuhle phakathi kwezongezo kunye ne-resins, kunye neentsalela ze-solvent ephezulu inokuchaphazela ukubambisana kweengubo kunye nokuguquguquka, ekhokelela ekuqhekekeni.
2.2 IiParameters zeNkqubo yeMveliso engafanelekanga
2.2.1 Ukuphambuka kweParameter yoKwaleka
Ulawulo olungafanelekanga lwesantya sokugquma, ubukhulu, okanye uxinzelelo lwencakuba kagqirha lunokubangela ukutyeba okungalinganiyo kokutyabeka (ukutenxa >± 3%). Iingubo ezityebileyo ezigqithisileyo zithandeka kuxinzelelo lwangaphakathi ngenxa yokuncipha okungahambelaniyo, ngelixa iingubo ezibhityileyo ngokugqithisileyo zisilela ukwenza umaleko opheleleyo okhuselayo.
2.2.2 Ulawulo lweNkqubo yokuNyanga kakubi
Amaqondo obushushu aphezulu ngokugqithisileyo okanye amaxesha amade ekunyangelweni komoya oshushu anokudityaniswa ngaphezulu kwengubo, ukwenza kube brittle; ubushushu obungonelanga okanye ixesha likhokelela kunyango olungaphelelanga kunye namandla aphantsi. Ukuqina okungafanelekanga kwe-UV okanye ixesha lokuvezwa kunokubangela ukunyanga okungalinganiyo okanye ukufudumeza kwendawo.
2.2.3 UkuSlitting okungafanelekanga kunye nokuPhelisa
Isantya esigqithileyo sokuqhawula okanye ukuxinana kunokubangela ukuqhekeka komphetho; Uxinzelelo olugqithileyo olumazongo lubeka i-coating phantsi koxinzelelo oluqhubekayo, ukwenza kube lula ukuba brittleness ngexesha lokugcinwa.
2.3 Ukungonelanga kweSubstrate Pretreatment
Ukungacoceki komphezulu kunye noburhabaxa kuchaphazela kakhulu ukunamathela kokugquma. Ukucoca okungaphezulu ngaphandle kokuchithwa kweekhemikhali okanye i-electrochemical oxidation ishiya i-oyile kunye neentsalela zothuli, buthathaka ukunamathela kokutyabeka. Uburhabaxa bomphezulu obungonelanga (amandla angaphezulu <35 mN/m) ikwathintela ukumanzisa okwaneleyo kunye nokusabalalisa kwengubo.
2.4 Imiba yokusingqongileyo
Amaqondo obushushu emveliso angaphantsi kwe 15°C okanye ukufuma ngaphezulu 80% kunokuchaphazela umgangatho wokwaleka kunye nokusebenza kakuhle kokunyanga. Ubushushu obugqithisileyo kunye nokuguquguquka kokufuma ngexesha lokugcinwa kunye nokuthutha kudala uxinzelelo lwe-thermal ngenxa ye-coefficients engahambelaniyo yokwandiswa kwe-thermal phakathi kwe-foil kunye ne-coating.. Iimpembelelo zomzimba okanye ukunyanzeliswa kunokubangela ngokuthe ngqo ukuba brittleness. Ukucoceka kwendawo yokuvelisa imveliso ivumela amasuntswana othuli ukuba enze amanqaku oxinzelelo, ukukhawuleza brittleness.
3. Amanyathelo oPhuculo lweNkqubo yokuBika ubuqhophololo
Itafile 3: IiParameters eziPhambili zoLawulo lokuPhuculwa kweNkqubo ye-Aluminiyam ye-Pharmaceutical
| Indawo yoPhuculo | IParameter yokulawula | IParameter ecetyiswayo/eMgangatho | Ukulawula Injongo |
|---|---|---|---|
| Iimpahla ezingekasilwa | Ukunyamezela ubunzima be-substrate | Ngaphakathi ±2μm | Qinisekisa ukufana kokugquma |
| Ukunyanzeliswa komphezulu we-substrate | ≥31 mN/m | Qinisekisa ukumanzisa okulungileyo | |
| Resin iglasi utshintsho lobushushu (Tg) | 20-40°C | Ukulinganisela ukuguquguquka kunye namandla | |
| Melt flow index ukwahluka kweresin yophawu lobushushu | ≤±10% | Qinisekisa uzinzo lwenkqubo | |
| Inkqubo yokwaleka | Isantya sokugquma | 10-15 m / yam | Qinisekisa ukufana kokugquma |
| Ukwaleka ubukhulu ukufana | Ukutenxa ≤±3% | Kuphephe ukugxininiswa koxinzelelo lwangaphakathi | |
| Ubunzima bokugquma | 2-5 g / m² | ||
| Inkqubo yoNyango | Ubushushu bomoya oshushu/ixesha | 80-100°C / 3-5 imiz | Qinisekisa ukudibanisa okupheleleyo, kuphephe ukuba brittleness |
| Ukuqina / ixesha lokunyanga kwe-UV | 80-120 mJ/cm² / 1-2 s | ||
| I-Substrate Pretreatment | Ukukhutshwa kweekhemikhali (ubushushu/ixesha) | 50-60°C / 1-2 imiz | Susa ngokucokisekileyo ioli |
| Electrochemical oxidation (amandla ombane/ixesha) | 10-15 V / 30-60 s | Ukuphucula amandla angaphezulu kunye noburhabaxa | |
| Uxinzelelo lwasemva konyango | ≥35 mN/m | Qinisekisa ukunamathela kokugquma okuphezulu | |
| Okusingqongileyo & Ugcino | Ubushushu bemekobume yemveliso/ukufuma | 20-25°C / 50-60% Rh | Qinisekisa uzinzo lwenkqubo |
| Indawo yokugcina iqondo lobushushu/ukufuma | 15-25°C / ≤60% RH | Thintela ukuguga kunye nokufunxa ukufuma |
3.1 Ukuphucula uKhetho lweMathiriyeli ekrwada kunye noLawulo
3.1.1 UKhetho lweSubstrate eNgqongileyo
Sebenzisa ubunyulu obuphezulu, ukungcola okuphantsi 8011/8021 ialloyi ezinonyamezelo ubukhulu obulawulwa ngaphakathi ±2 μm kunye noxinzelelo lomphezulu ≥31 mN/m. Kwiimveliso ezifunwa kakhulu, substrates ezinobukhulu ≥0.030 mm zingakhethwa, ngezinga lomngxuma ongezantsi 0.1 nge square metre nganye.
3.1.2 Ukuphucula iResin kunye noKhetho oloNgezelelweyo
Khetha iireyini ezinobushushu obuphakathi beglasi (20-40°C) kunye nokusabalalisa ubunzima beemolekyuli ezifanayo. I-resin esekelwe emanzini okanye i-UV-enyangekayo iyacetyiswa ukuba ithathe indawo yeentlobo ezisekelwe kwi-solvent. Ukunyibilika kwesalathiso sokwahluka kweereyini zokutywinwa kobushushu kufuneka kube ≤±10%. Lungiselela imixube eyongeziweyo, ezifana nokusebenzisa iiplasticizers ukuphucula ukuguquguquka kunye ne-silane coupling agents ukuqinisa ukunamathela, ukuqinisekisa ukuhambelana okongeziweyo.
3.1.3 Ukuseka iiNdlela zokuHlola izinto ezikrwada
Yomeleza uhlolo olungenayo, esweni ukuguquguquka kwe-resin, ukuhanjiswa kobunzima bemolekyuli, ukucoceka kwe-substrate, uburhabaxa, njl., ukuthintela izinto ezingafanelekanga ekungeneni kwimveliso.
3.2 Ukuphucula iiParameters zeNkqubo yeMveliso
3.2.1 Ulawulo lweNkqubo echanekileyo yoKutyabeka
Ukulawula isantya sokugquma kwi-10-15 m / min, uxinzelelo logqirha kwi-0.1-0.3 MPa, kunye nobunzima bokugquma kwi-2–5 g/m², Ukuqinisekisa ukutenxa ukutyeba okufanayo ≤±3%. Gcina izixhobo rhoqo ukuze uqinisekise ukufana kwengubo.
3.2.2 Ukuphucula IiParameters zeNkqubo yokuNyanga
Ukunyanga umoya oshushu kufuneka kulawulwe kwi-80-100 ° C imizuzu emi-3-5 kunye nesantya somoya esifana ne-1-2 m / s.; Ukuqina kokunyanga kwe-UV kufuneka kube yi-80–120 mJ/cm² imizuzwana eyi-1–2. Jonga kwaye uhlengahlengise iiparamitha ngexesha langempela.
3.2.3 Ukuphucula i-Slitting kunye ne-Winding Processes
Isantya sokuqhawula kufuneka sibe yi-5-10 m / min, ukunyanzeliswa koxinzelelo oluya kulawulwa kwi-50–100 N kusetyenziswa i-tension winding eqhubekayo. Vumela iikhoyili zamanxeba ukuba ziphumle iiyure ezingama-24-48 ukukhulula uxinzelelo lwangaphakathi. Ukuguquguquka kobushushu obuvale ubushushu kufuneka kulawulwe ngaphakathi kwe ±1°C.
3.3 Ukomeleza Iinkqubo zeSubstrate Pretreatment
Phumeza inkqubo epheleleyo yonyango lwangaphambili lwe “ukuhlanjululwa kweekhemikhali - ukuhlanjululwa kwamanzi - i-electrochemical oxidation - ukuhlanjululwa kwamanzi - ukomisa.” Ukunciphisa amafutha (50-60°C, 1–2 imizuzu) isusa amafutha; i-electrochemical oxidation (10-15 V, 30-60 imizuzwana) iphucula uburhabaxa kunye nomsebenzi; sebenzisa amanzi adiyoni ukuze uhlambe; ukomisa (80-90°C, 2–3 imizuzu) iqinisekisa ukoma komphezulu. Uxinzelelo lwe-substrate emva kokunyanga kufuneka lube ngu-≥35 mN/m.
3.4 Ukuphucula uLawulo lokusiNgqongileyo
3.4.1 Ukulawula iNdawo yeMveliso
Gcina ubushushu bendibano yocweyo bukwi-20–25°C, ukufuma okuhambelanayo kuma-50%–60%, kunye nokucoceka kwimigangatho yeBanga D ukunciphisa ukungcoliseka kothuli.
3.4.2 Ukuphucula uGcino kunye neeMeko zoThutho
Gcina iimveliso ezigqityiweyo kwindawo epholileyo (15-25°C), yomile (ukufuma ≤60%), kunye nendawo yokugcina umoya, ukuphepha ukukhanya kwelanga kunye nokupakisha ngokugqithiseleyo. Sebenzisa i-shockproof kunye nokupakishwa kobumanzi ngexesha lokuhamba, ukuphepha ukuguquguquka okugqithisileyo kobushushu/ukufuma kunye neempembelelo zoomatshini.
3.5 Ukuphucula iiNkqubo zokuHlola uMgangatho
3.5.1 Ukuseka iiNkqubo zoHlolo olupheleleyo
Yenza esweni kwi-intanethi yobunzima bokugquma kunye nokufana; ukuvavanya iimveliso ezigqityiweyo zokuguquguquka, ukuncamathela, amandla agqabhukileyo (≥98 kPa), Inqanaba lokuhambisa amanzi e-vapor (≤0.5 g/(m² · 20h)), njl.
3.5.2 Ukusebenzisa isiXhobo soVavanyo lobuNgcali
Zixhobise nge-pharmacopoeia-ethobelayo yokuqhuma abavavanyi (I-E.G., NPD-01B), sebenzisa i-headspace gas chromatography kuvavanyo lwentsalela ye-solvent, kunye nokusebenzisa iimicroscopes ukujonga i-microstructure yokwambathisa.
3.5.3 Ukusekwa koMgangatho wokuTraceability kunye neeNkqubo zoVavanyo loZinzo
Yenza iirekhodi zebhetshi zomgangatho wokulandeleka ngokupheleleyo. Ukuqhuba iimvavanyo zokuzinza rhoqo ukuvavanya ukusebenza kwengubo phantsi kweemeko ezahlukeneyo zokusingqongileyo.
4. Ukuqinisekiswa kokuPhuculwa kokuSebenza kunye neeNdlela zoShishino
4.1 Umzekelo woPhuculo oluSebenzayo
Emva kokuphumeza olu phuculo lungentla, inkampani iphumelele a 30% ukwanda kokuguquguquka kokugquma, a 25% ukuphuculwa kokubambelela, ukutenxa ukutenxa ukutyeba kobunzima ≤±2%, ukunyangwa kokugqiba izinga >99%, kunye nenqanaba lesiqinisekiso sonyango lwesubstrate 100%. Ireyithi ye-scrap ngenxa yokuqina kwehle ukusuka 8.5% ukuya ngaphantsi 0.3%, kunye nezinga lokufaneleka kwemveliso lifikelelwe 99.7%, ngamandla agqabhukileyo ukuhlangabezana neemfuno ze-pharmacopoeial. Ngokutshintshela kwiingubo ezisekelwe emanzini, Ukukhutshwa kwe-VOC kuye kwancitshiswa ngaphezulu 80%, ukungena ngempumelelo kwikhonkco lonikezelo lweenkampani eziphambili zamayeza.
Itafile 4: Ukuthelekiswa kweZalathi eziPhambili ngaphambi nasemva koPhuculo lweNkqubo kwiNkampani
| Isalathisi sokuSebenza esiPhambili | Ubume phambi koPhuculo | Ubume emva koPhuculo | Uphuculo/Isimo sokuThobela |
|---|---|---|---|
| Ukwaleka Ukuguquguquka | Iphantsi, ithanda ukuqhekeka | Iphuculwe kakhulu | Iphuculwe malunga 30% |
| Ukuncamathelisa ukwambathisa | Ayonelanga, utyekele kwi-delamination | Iqhina eliqinileyo | Iphuculwe malunga 25% |
| Ukwaleka Ukutyeba Uniformity | Ukutenxa >± 5% | Ukutenxa ≤±2% | Usukelo luphunyeziwe |
| Ireyithi yokuQeda yokuNyanga | ~95% | >99% | Umgangatho uzinzile kakhulu |
| I-Substrate Pretreatment Pass Rate | Ayizinzanga | 100% | Umgangatho womthombo ulawulwa |
| Ireyithi ye-Brittleness Scrap | 8.5% | <0.3% | Ukulahleka komgangatho kuncitshiswe kakhulu |
| Ireyithi yoMgangatho weMveliso xa iyonke | ~91% | 99.7% | Ihlangabezana neemfuno zabathengi abaphezulu |
| Qhoboza Amandla | Ngokuyinxenye ngezantsi 98 kPa | Yonke ≥98 kPa | 100% ukuthobela Pharmacopoeia yaseTshayina |
| Uncedo lwendalo esingqongileyo (IiVOCs) | Ukusebenzisa i-solvent-based coatings | Ukusebenzisa iingubo ezisekelwe emanzini | Ukukhutshwa kuncitshiswe nge >80% |
4.2 IiNdlela zoPhuhliso lweShishini
4.2.1 Ukwenziwa kweGreening of Coating Technologies
Isekelwe emanzini, I-UV-inonyangeka, kunye nee-electron beam-curable coatings ezine-VOC eziphantsi okanye zero ziya kuthatha indawo yeemveliso ezisekelwe kwi-solvent.
4.2.2 Uphuhliso oluSebenzayo malunga nokuChaneka nobukrelekrele
Iingubo ziguqukela kubukrelekrele bokuchasana nenkohliso, into-enye-ikhowudi yokulandeleka, ukhuseleko lokukhanya oluguqukayo, kunye nokuqonda okuhlakaniphileyo ukuhlangabezana neemfuno zokukhusela zamachiza asebenzayo kakhulu.
4.2.3 Ukugxininisa iMimiselo yoShishino
I Pharmacopoeia yaseTshayinaimigangatho iyaqhubeka ukuya phambili, ngovavanyo olunabela kwi-microstructure, ukubonakaliswa kweekhemikhali, kunye ne-biocompatibility, inkqubo yokuqhuba kunye nokuphuculwa komgangatho wolawulo kumashishini.
5. Ukuqukumbela
I-brittleness yokwambathisa kwifoyile ye-aluminiyam ye-pharmaceutical sisiphoso somgangatho esibangelwa yimiba emininzi, kuquka imathiriyeli ekrwada, iinkqubo, unyango lwangaphambili, kunye neemeko zokusingqongileyo, ukwenza izoyikiso kukhuseleko lweziyobisi, ukuthobela iqumrhu, kunye nomdla wezoqoqosho. Ngokulungiselela kakuhle imathiriyeli ekrwada, ulawulo oluchanekileyo iiparamitha zenkqubo, ukomeleza i-substrate pretreatment, ukulawula ngokungqongqo iimeko zokusingqongileyo, kunye nokuphucula iinkqubo zokuhlola umgangatho, umngcipheko we-brittleness unokupheliswa ngokufanelekileyo, ukwandisa ukuthembeka kwemveliso.
Kwilixa elizayo, amashishini kufuneka alandele iindlela zoshishino ezibhekiselele kuhlaza, ukuchaneka, kunye nokusebenza, ukwandisa R&D utyalo-mali, rhoqo uphuculo lwenkqubo, ukubambelela ngokungqongqo kwi-pharmacopoeia kunye nemigangatho ehambelanayo, kunye nokuphucula iinkqubo zokulawula umgangatho ukuqinisekisa ukhuseleko lwamachiza ngeemveliso ezikumgangatho ophezulu kunye nokunyusa umgangatho woshishino ngokubanzi.